Differential activation of P-TEFb complexes in the development of cardiomyocyte hypertrophy following activation of distinct GPCRs
Ryan Martin, Ya‐Lin Sun, Sarah MacKinnon, Luca Cuccia, Viviane Pagé, Terence E. Hébert, Jason C. Tanny
The paper investigates how different GPCRs regulate P-TEFb complexes in cardiomyocyte hypertrophy, showing distinct roles for SEC and Brd4 in response to 1-AR and ETR activation.
Molecular and Cellular Biology · Apr 22, 2020Peer-reviewedMolecular Biology