2B4 co-engagement promotes serial degranulation and killing by human NK cells
Luca Kröll, Mina Sandusky, Michele Saretzki, Maren Claus, Sabine Wingert, Jens Alexander Niemann, Carsten Watzl
The paper identifies how combinations of ligand-receptor interactions regulate NK cell activation, showing that 2B4 co-engagement enhances serial degranulation and killing.
bioRxiv · Aug 5, 2026 · PreprintImmunology