Supramolecular Enzyme-Peptide Gels for Localized Therapeutic Biocatalysis
Madeline J Fuchs, Lucas Melgar, Bethsymarie Soto Morales, Dillon T. Seroski, Jennifer A Simonovich, Isabella Pinto, Chen Lu, Gianna Scibilio, Renjie Liu, Abigail M. Ziegler, Juanpablo Olguin, Arun Wanchoo, Ayumi Shigemoto, Dorina Avram, Benjamin George Keselowsky, Gregory A. Hudalla
This paper develops a supramolecular enzyme-peptide gel platform for localized therapeutic biocatalysis, showing improved retention and efficacy in treating gout.
bioRxiv · Sep 6, 2024 · PreprintBioengineering