The C. elegans endonuclease NUC-1 acts in engulfing cells to degrade the apoptotic cell DNA
Jonathan Pickett, Xianghua Liu, Lucia Chiao, Omar Cruz Ramírez, Lathan Lucas, Zheng Zhou
The paper clarifies that NUC-1, a DNase in C. elegans, degrades apoptotic cell DNA in engulfing cells, not in the apoptotic cell nucleus.
bioRxiv · Aug 23, 2026 · PreprintGenetics