Identification of pleiotropic genes and biological mechanisms underlying the shared genetic component between asthma, neuropsychiatric disorders, and substance use behaviors
Haibo Huang, Raphaël Vernet, Lucie Troubat, Christophe Linhard, Lucas M. P. Chataigner, Yuka Suzuki, Stephan Fischer, Hugues Aschard, Florence Démenais, Emmanuelle Bouzigon, Hanna Julienne
The paper identifies pleiotropic genes and mechanisms linking asthma, neuropsychiatric disorders, and substance use behaviors through multi-trait GWAS and single-cell transcriptomics.
medRxiv · Oct 19, 2026 · PreprintGenetic & Genomic Medicine