Author

Florence Démenais

InsermORCID 0000-0001-8361-0936Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 2 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:GWAS summary statistics· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 2 Research Focus:polygenic risk· 2 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Christopher Ian AmosiD· 2 shared David Timothy BishopiD· 2 shared Haoyu ZhangiD· 2 shared Jiyeon ChoiiD· 2 shared Katherine L. NathansoniD· 2 shared Mai XuiD· 2 shared Mark Martin IlesiD· 2 shared Matthew H. LawiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetic & Genomic Medicine

Christopher Ian AmosORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintOct 19, 2026

Identification of pleiotropic genes and biological mechanisms underlying the shared genetic component between asthma, neuropsychiatric disorders, and substance use behaviors

Haibo Huang, Raphaël Vernet, Lucie Troubat…·Hanna Julienne

The paper identifies pleiotropic genes and mechanisms linking asthma, neuropsychiatric disorders, and substance use behaviors through multi-trait GWAS and single-cell transcriptomics.

DOI 10.64898/2026.10.16.26364574

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintOct 15, 2026

Melanoma germline genetics: immune, cancer driver, and Wnt signaling genes

G J M Shanika R Jayasinghe, Jianxin Shi, Rohit Thakur…·Nhan Do

This paper identifies 116 risk loci for melanoma through GWAS, links susceptibility to immunity and Wnt signaling, and develops a PRS improving risk prediction.

DOI 10.64898/2026.10.14.26365068

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsNature CommunicationsPeer-reviewedJul 3, 2020

Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers

Yan Zhang, Amber N. Hurson, Haoyu Zhang…·Colon Cancer Family Registry (CCFR)

This study assesses polygenicity and risk prediction using common variants across 14 cancers, finding varying numbers of susceptibility variants and risk score effectiveness.

137 citationstop 1%

humanGWAS summary statistics

𝕏 PostBluesky

GenomicsNature CommunicationsPeer-reviewedJun 1, 2020

Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion

Jiyeon Choi, Tongwu Zhang, Andrew H. Vu…·Kevin M. Brown

The paper identifies multiple melanoma susceptibility genes and variants by integrating MPRA with eQTL data, revealing MX2's role in melanoma promotion.

139 citationstop 1%

humanzebrafish

𝕏 PostBluesky