GapR is a nucleoid-associated protein that stiffens and overtwists DNA to promote transcription and replication
Xinjue Wei, Lucy M. Kwiatkowski, Ryo Kawamura, John F. Marko, Monica S. Guo
This study investigates GapR's role in DNA mechanics and transcription regulation using biophysical and computational methods, revealing its dual effects on DNA structure and transcription.
bioRxiv · Jan 14, 2026 · PreprintMolecular Biology