Monica S. Guo

This study investigates GapR's role in DNA mechanics and transcription regulation using biophysical and computational methods, revealing its dual effects on DNA structure and transcription.

This study investigates how post-translational modifications on adenovirus protein VII affect its function during early and late infection stages, revealing their role in localization, transcription, and protein interactions.

This study investigates how positive and negative supercoiling influence 3D genome organization in E. coli using Hi-C and ChIP-seq data, finding positive supercoiling enhances spatial contacts more than negative supercoiling.

The paper introduces GapR-seq, a method to map positive supercoiling in genomes, and finds it widespread, associated with transcription and specific genomic features in E. coli and yeast.