Low-complexity domains adhere by reversible amyloid-like interactions between kinked β-sheets
Michael P. Hughes, Michael R. Sawaya, Lukasz Goldschmidt, Jose A. Rodriguez, Duilio Cascio, Tamir Gonen, David S. Eisenberg
The paper reports atomic structures of low-complexity domains showing reversible amyloid-like interactions, identifies hundreds of potential segments in the human proteome, and links them to dynamic intracellular bodies.
bioRxiv · Jun 22, 2017 · PreprintBiochemistry