Luqman O. Ajisafe

Structural insights into target detection by the S. marcescens type III CRISPR complex and its deployment inSNP identification

The paper determines the structure of S. marcescens Type III CRISPR complex and shows it can detect SNPs in human transcripts associated with sickle cell disease.

Two dynamic, N-terminal regions are required for function in Ribosomal RNA Adenine Dimethylase family members

The paper identifies two N-terminal regions in RRAD enzymes critical for function, showing they promote rRNA binding and substrate positioning for methylation.