Guidestar: a spike-in approach to improve RNA detection accuracy in imaging-based spatial transcriptomics
Jazlynn Xiu Min Tan, Lurong Wang, Wan Yi Seow, Jeeranan Boonruangkan, Mike Huang, Jiamin Toh, Kok Hao Chen, Nigel Chou
Guidestar improves RNA detection accuracy in spatial transcriptomics by using spike-in controls to assess and enhance decoding algorithms.
bioRxiv · Jan 9, 2025 · PreprintGenomics