The Notch Ligand Jagged1 is Required for the Formation, Maintenance, and Survival of Hensen Cells in the Mouse Cochlea
Elena Chrysostomou, Luyi Zhou, Yuanzhao L. Darcy, Kaley A. Graves, Angelika Doetzlhofer, Brandon C. Cox
This study shows that Jagged1 is essential for forming and maintaining Hensen cells in the mouse cochlea, with its loss leading to cell death or conversion into Claudius cells.
Journal of Neuroscience · Oct 30, 2020Peer-reviewedDevelopmental Biology