FUN-LDA: A latent Dirichlet allocation model for predicting tissue-specific functional effects of noncoding variation
Daniel Backenroth, Zihuai He, Krzysztof Kiryluk, Valentina Boeva, Lynn Pethukova, Ekta Khurana, Angela M. Christiano, Joseph D. Buxbaum, Iuliana Ionita‐Laza
FUN-LDA predicts tissue-specific functional effects of noncoding variants by integrating epigenetic data, showing higher accuracy than existing methods in eQTL and GWAS analyses.
bioRxiv · Aug 2, 2017 · PreprintBioinformatics