Protein kinases mediate anti-inflammatory effects of cannabidiol and estradiol against high glucose in cardiac sodium channels
This study shows that inflammation and PK-A/PK-C activation mediate high glucose-induced Nav1.5 gating defects, which are reversed by CBD and E2, suggesting a potential therapeutic role for CBD in diabetic arrhythmias.
bioRxiv · Nov 23, 2020Pharmacology & Toxicology