Small volume blood-brain barrier opening in macaques with a 1 MHz ultrasound phased array
T. J. Manuel, M. K. Sigona, M. A. Phipps, J. Kusonose, H. Luo, P.-F. Yang, A. T. Newton, J. C. Gore, W. Grissom, L. M. Chen, C. F. Caskey
This paper demonstrates small volume BBB opening in macaques using a 1 MHz ultrasound phased array and characterizes safe pressure ranges and correlation between simulations and measurements.
bioRxiv · Mar 2, 2023Bioengineering