Author

M. A. Saper

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Kelley· 1 shared A. Sulpizio· 1 shared F. Cava· 1 shared J.-H. Shin· 1 shared L. Alvarez· 1 shared S. Murphy· 1 shared T. Doerr· 1 shared Y. Mao· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

A. Kelley

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1 paper

Recent·Most cited

Structural basis of peptidoglycan endopeptidase regulation

J.-H. Shin, A. Sulpizio, A. Kelley, L. Alvarez, S. Murphy, F. Cava, Y. Mao, M. A. Saper, T. Doerr

This study solves the crystal structure of ShyA, a peptidoglycan endopeptidase, revealing a regulatory mechanism involving conformational changes that activate its catalytic activity.

bioRxiv · Nov 17, 2019Microbiology