Author

M. A. Savageau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Evolutionary Biology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

M. A. Valderrama-Gomez· 3 shared B. J. Cole· 1 shared C. Juliano· 1 shared C. N. Shulse· 1 shared D. E. Dickel· 1 shared D. Han· 1 shared G. M. Turco· 1 shared H. Vahldick· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBioengineering

M. A. Valderrama-Gomez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Phenotype-Centric Modeling for Rational Metabolic Engineering

M. A. Valderrama-Gomez, M. A. Savageau

This paper introduces a phenotype-centric modeling approach for metabolic engineering, demonstrating its ability to identify beneficial interventions and propose improved strains for the amorphadiene biosynthetic network.

bioRxiv · Nov 26, 2021Bioengineering

Molecular Systems Predict Equilibrium Distributions of Phenotype Diversity Available for Selection

M. A. Valderrama-Gomez, M. A. Savageau

The paper introduces a theoretical framework to predict phenotype diversity distributions and mutation rates using Systems Design Space methods, applied to a primordial circadian clock system.

bioRxiv · May 27, 2021 · PreprintEvolutionary Biology

TaxisPy: A Python-based Software for the Quantitative Analysis of Bacterial Chemotaxis

M. A. Valderrama-Gomez, R. A. Schomer, M. A. Savageau, R. E. Parales

TaxisPy is a Python-based software for analyzing bacterial chemotaxis, estimating average tumbling frequency from video data and demonstrating its use on Pseudomonas putida and Escherichia coli.

bioRxiv · Feb 6, 2020Microbiology

Molecular Mechanisms Driving Bistable Switch Behavior in Xylem Cell Differentiation

G. M. Turco, J. Rodriguez-Medina, S. Siebert, D. Han, H. Vahldick, C. N. Shulse, B. J. Cole, C. Juliano, D. E. Dickel, M. A. Savageau, S. M. Brady

The paper models the molecular mechanisms of bistable switching in xylem cell differentiation using whole root and single-cell data, identifying VND7's role and a novel regulatory cycle.

bioRxiv · Feb 8, 2019Plant Biology