Dysregulated DnaB unwinding induces replisome decoupling and daughter strand gaps that are countered by RecA polymerization
M. S. Behrmann, H. M. Perera, M. U. Welikala, J. E. Matthews, M. A. Trakselis
This paper investigates how dysregulated DnaB unwinding in E. coli leads to DNA damage and shows that RecA filamentation helps repair daughter strand gaps and prevent DNA breaks.
bioRxiv · Jun 26, 2023 · PreprintBiochemistry