Author

W. C. Griffin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. R. McKinzey· 2 shared K. N. Klinzing· 2 shared A. Rajkovic· 1 shared A. Schepartz· 1 shared E. P. Jeffries· 1 shared F. A. Cruz Navarrete· 1 shared I. Knudson· 1 shared J. L. Alejo· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

D. R. McKinzey

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

β-amino acids reduce ternary complex stability and alter the translation elongation mechanism

F. A. Cruz Navarrete, W. C. Griffin, Y.-C. Chan, M. I. Martin, J. L. Alejo, S. K. Natchiar, I. Knudson, R. B. Altman, A. Schepartz, S. J. Miller, S. C. Blanchard

This study investigates how β-amino acid isomers affect ternary complex stability and translation elongation by analyzing their impact on ribosome function and EF-Tu interactions.

bioRxiv · Feb 24, 2024Biochemistry

A novel multi-functional role for the MCM8/9 helicase complex in maintaining fork integrity during replication stress

W. C. Griffin, D. R. McKinzey, K. N. Klinzing, R. Baratam, M. A. TRAKSELIS

This study identifies novel multifunctional roles for MCM8/9 in maintaining replication fork integrity during normal progression and under stress.

bioRxiv · Dec 8, 2021Cell Biology

Motifs of the C-terminal Domain of MCM9 Direct Localization to Sites of Mitomycin-C Damage for RAD51 Recruitment

D. R. McKinzey, S. Gomanthinayagam, W. C. Griffin, K. N. Klinzing, E. P. Jeffries, A. Rajkovic, M. TRAKSELIS

This study identifies two motifs in the C-terminal domain of MCM9 that mediate its localization to DNA damage sites and recruitment of RAD51 for repair.

bioRxiv · Jul 29, 2020Biochemistry