Mechanistic insights into Zika virus NS3 helicase inhibition by Epigallocatechin-3-gallate
D. Kumar, N. Sharma, M. Aarthy, S. Singh, R. Giri
This study investigates how EGCG inhibits ZIKV NS3 helicase through molecular docking, simulation, and enzymatic assays, showing significant NTPase inhibition with an IC50 of 295.7 nM.
bioRxiv · Jan 26, 2019Biochemistry