Author

M. Ahsan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

G. Palermo· 2 shared A. M. D'Ordine· 1 shared A. Saha· 1 shared C. Chanez· 1 shared E. Skeens· 1 shared G. Jogl· 1 shared G. P. Lisi· 1 shared M. Jinek· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

G. Palermo

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Author profile →

2 papers

Recent·Most cited

High-Fidelity, Hyper-Accurate, and Evolved Mutants Rewire Atomic Level Communication in CRISPR-Cas9

E. Skeens, S. Sinha, M. Ahsan, A. M. D'Ordine, G. Jogl, G. Palermo, G. P. Lisi

The paper investigates how specific mutations in the Rec3 domain of CRISPR-Cas9 variants affect structural dynamics and allosteric communication to enhance specificity.

bioRxiv · Aug 25, 2023 · PreprintBiophysics

An Alpha-helical Lid Guides the Target DNA toward Catalysis in CRISPR-Cas12a

A. Saha, M. Ahsan, P. R. Arantes, M. Schmitz, C. Chanez, M. Jinek, G. Palermo

This study reveals how the alpha-helical lid in CRISPR-Cas12a guides the DNA target strand toward the RuvC catalytic core through molecular dynamics simulations and experiments.

bioRxiv · Sep 5, 2022Biophysics