Identification and Age-dependent Increase of Platelet Biased Human Hematopoietic Stem Cells
M. Aksoz, G.-A. Gafencu, B. S. Stoilova, M. Buono, Y. Meng, N. A. Jakobsen, M. Metzner, S.-A. Clark, R. Beveridge, S. Thongjuea, P. Vyas, C. Nerlov
The paper identifies platelet-biased human hematopoietic stem cells (HSCs) and shows their proportion and transcriptional platelet priming increase with age.
bioRxiv · Jan 14, 2022 · PreprintCell Biology