Streptolysin production and activity is central to in vivo pathotype and disease outcome in GAS infections
J. Clarke, M. Baltazar, M. Alsahag, S. Panagiotou, M. Pouget, W. A. Paxton, G. Pollakis, D. Everett, N. French, A. Kadioglu
This study shows that streptolysin O (SLO) production and activity determine the pathotype and disease outcome in Group A Streptococcus (GAS) infections, with implications for therapeutic strategies.
bioRxiv · Jun 28, 2019 · PreprintMicrobiology