Genotype-immunophenotype relationships in NPM1-mutant AML clonal evolution uncovered by single cell multiomic analysis
Morgan Drucker, Darren Lee, M. B. Bowman, Xuan Zhang, Bailee Nicole Kain, Deedra Nicolet, Roopsha Bandopadhyay, Varsha Singh, Zhe Wang, Richard Maury Stone, Caner Saygin, Krzysztof Mrózek, Andrew J. Carroll, Daniel T. Starczynowski, Ross L. Levine, , Linde A. Miles
This study uses single-cell multiomic analysis to reveal genotype-immunophenotype relationships and clonal evolution in NPM1-mutant AML across disease stages.
Blood · Apr 8, 2026Peer-reviewedCancer Biology