M. Burman

Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA

The paper introduces COMBI-Tweez, a tool combining optical and magnetic tweezers with fluorescence microscopy to study the structural dynamics of single chiral biopolymers like DNA under mechanical forces.

Atomic description of the reciprocal action between supercoils and melting bubbles on linear DNA

The paper uses molecular dynamics simulations to study DNA supercoiling and melting bubbles, revealing a new state in negative supercoiling where denaturation bubbles form in AT-rich regions.

Rolling Circle RNA Synthesis Catalysed by RNA

This study demonstrates RNA-catalysed rolling circle synthesis on circular RNAs, showing strand displacement and concatemeric product formation, suggesting RNA can support complex replication pathways.

SerraNA: a program to determine nucleic acids elasticity from simulation data

SerraNA calculates elastic parameters of nucleic acids from simulation data, revealing sequence-dependent elasticity and global bendability from local bending angles.