ESCRT recruitment by the inner nuclear membrane protein Heh1 is regulated by Hub1-mediated alternative splicing
M. Capella, L. Martin Caballero, B. Pfander, S. Braun, S. Jentsch
The paper shows that Hub1-mediated alternative splicing of HEH1 generates Heh1-S, which prevents excessive ESCRT recruitment to the nuclear envelope and maintains NE integrity.
bioRxiv · Jun 25, 2020Cell Biology