Author

M. D. Blower

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:statistical model· 1

Frequent Co-Authors

W. Wang· 2 shared A. D. Echard· 1 shared A. Jambhekar· 1 shared A. Presle· 1 shared A. R. Skop· 1 shared C. Moravec· 1 shared C. Perea-Resa· 1 shared E. Kurt· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

W. Wang

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4 papers

Recent·Most cited

The midbody and midbody remnant are assembly sites for RNA and active translation

S. Park, R. D. Dahn, E. Kurt, A. Presle, K. VandenHeuvel, C. Moravec, A. Jambhekar, O. K. Olukoga, J. D. Shepherd, A. D. Echard, M. D. Blower, A. R. Skop

This paper identifies the midbody and its remnants as sites of RNA assembly and active translation, proposing them as novel RNA-based organelles involved in intercellular communication.

bioRxiv · Nov 1, 2022 · PreprintCell Biology

Differential nuclear import determines lncRNA inheritance following mitosis

M. D. Blower, W. Wang, J. Sharp

The paper investigates RNA inheritance after mitosis, finding that half of nuclear RNAs are inherited transcription-independently, with snRNAs like U2 being retained while lncRNAs like NEAT1 and MALAT1 are not.

bioRxiv · Oct 6, 2022Cell Biology

Prophase removal of chromosome-associated RNAs facilitates anaphase chromosome segregation

J. A. Sharp, W. Wang, M. D. Blower

This study shows that Aurora-B phosphorylates SAF-A to remove RNA from chromosomes during prophase, preventing anaphase segregation errors.

bioRxiv · Oct 21, 2019 · PreprintCell Biology

Cohesin removal reprograms gene expression upon mitotic entry

C. Perea-Resa, L. Bury, I. Cheeseman, M. D. Blower

This study shows that cohesin removal during prophase is necessary for RNAPII dissociation from chromosome arms and reprogramming gene expression during mitosis.

bioRxiv · Jun 26, 2019Cell Biology