A robust SARS-CoV-2 replication model in primary human epithelial cells at the air liquid interface to assess antiviral agents
T. N. D. Do, K. Donckers, L. Vangeel, A. K. Chatterjee, P. A. Gallay, M. D. Bobardt, J. P. Bilello, T. Cihlar, S. De Jonghe, J. Neyts, D. Jochmans
This study develops a SARS-CoV-2 replication model using primary human airway epithelial cells to test antiviral agents, finding that remdesivir and interferons inhibit replication while AT-511 does not.
bioRxiv · Mar 25, 2021Microbiology