A novel tool for monitoring endogenous human MYC transcription and translation by EGFP tag insertion at the 3’ end using CRISPR-Cas9 genome editing
The paper develops a CRISPR-Cas9-based system to monitor endogenous MYC transcription and translation in colorectal cancer cells using EGFP tagging, enabling high-throughput genetic and drug screening.
bioRxiv · Apr 9, 2019 · PreprintCancer Biology