LIPIDS MODULATE THE DYNAMICS OF GPCR:β-ARRESTIN INTERACTION
A. A. S. GOMES, M. DI MICHELE, R. A. ROESSNER, M. DAMIAN, P. M. BISCH, N. SIBILLE, M. LOUET, J.-L. BANERES, N. FLOQUET
This study shows that PI(4,5)P2 modulates the orientation and receptor interaction of β-arrestin 1 through its interaction with the C-edge loop.
bioRxiv · Mar 16, 2024Biophysics