Author

M. du Plessis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:phylogenetics / evolution· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

A. von Gottberg· 3 shared L. Mcgee· 3 shared S. D. Bentley· 3 shared A. Skoczynska· 2 shared B. Beall· 2 shared B. J. Metcalf· 2 shared L. Bell· 2 shared M. Antonio· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersEvolutionary Biology

A. von Gottberg

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Author profile →

5 papers

Recent·Most cited

Enamel proteins reveal biological sex and genetic variability within southern African Paranthropus

P. P. Madupe, C. Koenig, I. Patramanis, P. L. Rüther, N. Hlazo, M. Mackie, M. Tawane, J. Krueger, A. J. Taurozzi, G. B. Troche, J. Kibii, R. Pickering, M. R. Dickinson, Y. Sahle, D. Kgotleng, , E. Cappellini

This study uses enamel proteomics to determine biological sex and assess intraspecific variation in Paranthropus robustus from South Africa, supporting the idea that morphological variation may reflect taxonomic diversity.

bioRxiv · Jul 3, 2023Evolutionary Biology

Geographic migration and vaccine-induced fitness changes of Streptococcus pneumoniae

S. Belman, N. Lefrancq, S. A. Nzenze, S. L. Downs, M. du Plessis, S. W. Lo, The Global Pneumococcal Sequencing Consortium, L. Mcgee, S. A. Madhi, A. von Gottberg, S. D. Bentley, H. Salje

The paper uses genomic data to study geographic spread and fitness changes in Streptococcus pneumoniae strains before and after vaccine implementation.

bioRxiv · Jan 18, 2023 · PreprintEvolutionary Biology

Microbial function and genital inflammation in young South African women at high risk of HIV infection

A. Alisoltani, M. T. Manhanzva, M. G. Potgieter, C. Balle, L. Bell, E. Ross, A. Iranzadeh, M. du Plessis, N. Radzey, Z. McDonald, B. Calder, I. Allali, N. Mulder, S. Dabee, S. Barnabas, , L. Masson

This study uses metaproteomics to link microbial function and inflammation in the female genital tract of South African women at high HIV risk, finding that reduced cell wall organization and peptidoglycan biosynthesis are associated with high inflammation.

Microbiome · Nov 21, 2020Peer-reviewedMicrobiology

A novel mosaic tetracycline resistance gene tet(S/M) detected in a multidrug-resistant pneumococcal CC230 lineage that underwent capsular switching in South Africa

S. W. Lo, R. A. Gladstone, A. J. van Tonder, M. du Plessis, J. E. Cornick, P. A. Hawkins, S. A. Madhi, S. A. Nzenze, R. Kandasamy, K. Ravikumar, N. Elmdaghri, B. Kwambana-Adams, S. C. G. Almeida, A. Skoczynska, E. Egorova, , A. von Gottberg

The paper identifies a novel tetracycline resistance gene tet(S/M) in a multidrug-resistant pneumococcal lineage in South Africa and links its spread to HIV treatment and vaccine implementation.

bioRxiv · Jul 30, 2019 · PreprintMicrobiology

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci

T. Azarian, P. Mitchell, M. Georgieva, C. M. Thompson, A. Ghoulia, A. J. Pollard, A. von Gottberg, M. du Plessis, M. Antonio, B. A. Kwambana-Adams, S. C. Clarke, D. Everett, J. Cornick, E. Sadowy, W. Hryniewicz, , W. P. Hanage

This study analyzes global serotype 3 pneumococcal isolates to show a recent emergence of Clade II with antibiotic resistance and antigenic diversity, not linked to PCV13 usage.

bioRxiv · Jun 27, 2018Evolutionary Biology