W. P. Hanage

Enterobacteriaceae isolated from patients share antibiotic resistance conferring plasmids recently acquired from those isolated from sinks in the same treatment room

The paper identifies shared antibiotic resistance plasmids between patient and sink isolates, suggesting plasmid transmission from sinks to patients.

Negative frequency-dependent selection and asymmetrical transformation stabilise multi-strain bacterial population structures

The paper tests whether negative frequency-dependent selection and asymmetrical recombination can explain the stability of multi-strain bacterial populations using simulations and genomic data.

Predicting evolution using frequency-dependent selection in bacterial populations

The paper predicts changes in pneumococcal populations after vaccination by analyzing accessory gene frequencies under negative frequency-dependent selection.

Choosing Your Battles: Which Resistance Genes Warrant Global Action?

This paper develops a framework to prioritize antibiotic resistance genes (ARGs) based on risk factors and identifies high-risk ARGs for global action.

Horizontal gene transfer rate is not the primary determinant of observed antibiotic resistance frequencies in Streptococcus pneumoniae

The study examines antibiotic resistance frequencies in Streptococcus pneumoniae and finds that horizontal gene transfer rates are not the main factor influencing these frequencies.

Fine-scale haplotype structure reveals strong signatures of positive selection in a recombining bacterial pathogen

The paper identifies strong signatures of positive selection in Neisseria gonorrhoeae by analyzing fine-scale haplotype structure and linkage patterns between nonsynonymous alleles.

Global emergence and population dynamics of divergent serotype 3 CC180 pneumococci

This study analyzes global serotype 3 pneumococcal isolates to show a recent emergence of Clade II with antibiotic resistance and antigenic diversity, not linked to PCV13 usage.

Weak epistasis may drive adaptation in recombining bacteria

This study shows that weak epistasis can influence adaptation in recombining bacteria, even when recombination is frequent, due to limited transfer of genetic segments.