The 4T1 breast carcinoma model possesses hybrid epithelial/mesenchymal traits linked to a highly metastatic phenotype
M. E. Herndon, K. Gibson-Corley, L. L. Wallrath, M. Henry, C. S. Stipp
This study investigates E-cadherin's role in 4T1 breast carcinoma metastasis, finding that E-cadherin is retained and does not determine metastatic capacity, with cells displaying hybrid epithelial/mesenchymal traits.
bioRxiv · Feb 2, 2024 · PreprintCancer Biology