Author

K. Gibson-Corley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

N. Borcherding· 2 shared A. Cox· 1 shared A. G. Rux· 1 shared A. J. Kwiatkowski· 1 shared A. J. Toepp· 1 shared A. K. Mangalam· 1 shared A. Kumar Kushwaha· 1 shared A. Leal Lima· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

N. Borcherding

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy

T. L. Sheehy, A. J. Kwiatkowski, K. Arora, B. R. Kimmel, J. A. Schulman, K. Gibson-Corley, J. T. Wilson

This paper develops SAPCon, a polymer-drug conjugate that activates the STING pathway in tumors, enhancing immunotherapy efficacy by promoting an immunogenic microenvironment and improving tumor growth inhibition.

bioRxiv · Mar 23, 2024Bioengineering

The 4T1 breast carcinoma model possesses hybrid epithelial/mesenchymal traits linked to a highly metastatic phenotype

M. E. Herndon, K. Gibson-Corley, L. L. Wallrath, M. Henry, C. S. Stipp

This study investigates E-cadherin's role in 4T1 breast carcinoma metastasis, finding that E-cadherin is retained and does not determine metastatic capacity, with cells displaying hybrid epithelial/mesenchymal traits.

bioRxiv · Feb 2, 2024 · PreprintCancer Biology

The distinct roles of MSH2 and MLH1 in basal-like breast cancer and immune modulation

T. I. Tithi, J. Mo, N. Borcherding, S. Jo, E. Cho, K. E. Cash, M. Honda, L. Wang, K. K. Ahmed, K. Shirlekar, L. Chen, R. Weigel, H. Kates, K. Gibson-Corley, M. Spies, , W. Zhang

This study identifies distinct roles of MSH2 and MLH1 in basal-like breast cancer, showing MSH2 promotes metastasis while MLH1 enhances it, and reveals MSH2's role in immune modulation through IFNAR1 regulation.

bioRxiv · Jul 20, 2023 · PreprintCancer Biology

IL-17A-mediated alterations in gut microbiota composition particularly changes in Prevotella abundance, impact Treg function in CNS Autoimmunity

S. K. Shahi, S. Ghimire, S. N. Jensen, P. Lehman, A. G. Rux, T.-A. Turner, N. Borcherding, K. Gibson-Corley, S. M. Ganesan, N. J. Karandikar, A. K. Mangalam

This study shows that IL-17A deficiency in mice leads to increased Tregs and beneficial gut microbes like Prevotella, reducing MS-like disease severity.

bioRxiv · Apr 22, 2022 · PreprintImmunology

Leishmania infantum xenodiagnosis from vertically infected dogs reveals significant skin tropism

B. M. Scorza, K. G. Mahachi, A. Cox, A. J. Toepp, A. Leal Lima, A. Kumar Kushwaha, P. Kelly, C. Menenses, G. Wilson, K. Gibson-Corley, L. Bartholomay, S. Kamhawi, C. A. Petersen

This study shows vertically infected dogs transmit Leishmania infantum to sand flies more effectively when they have moderate disease, with higher skin parasite loads correlating strongly with sand fly infection.

bioRxiv · Apr 8, 2021Microbiology