Author

M. E. Patti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:snRNA-seq· 2 Approach:statistical model· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Gupta· 2 shared A. M. Streets· 2 shared F. Shamsi· 2 shared Y.-H. Tseng· 2 shared A. M. Cypess· 1 shared A. P. White· 1 shared G. F. Dorlhiac· 1 shared N. Altemose· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersBioengineering

A. Gupta

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2 papers

Recent·Most cited

Mapping the temporal transcriptional landscape of human white and brown adipogenesis using single-nuclei RNA-seq

A. Gupta, F. Shamsi, M. E. Patti, Y.-H. Tseng, A. M. Streets

This study maps the temporal transcriptional changes during human white and brown adipogenesis using snRNA-seq, revealing key regulatory dynamics and adipogenic features in health and obesity.

bioRxiv · May 30, 2022Bioengineering

Characterization of transcript enrichment and detection bias in single-nuclei RNA-seq for mapping of distinct human adipocyte lineages

A. Gupta, F. Shamsi, N. Altemose, G. F. Dorlhiac, A. M. Cypess, A. P. White, M. E. Patti, Y.-H. Tseng, A. M. Streets

This study compares snRNA-seq and scRNA-seq in adipose tissue, showing snRNA-seq can identify cell types but has transcript enrichment and detection biases that require normalization.

bioRxiv · Mar 24, 2021Bioengineering