Author

M. E. Romero

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Organism:virus· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

J. Yu· 2 shared A. M. Keerthi· 1 shared C. Long· 1 shared D. La Rocco· 1 shared D. Xu· 1 shared S. J. McElhenney· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBiophysics

J. Yu

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2 papers

Recent·Most cited

Trapping non-cognate nucleotide upon initial binding for replication fidelity control in SARS-CoV-2 RNA dependent RNA polymerase

M. E. Romero, S. J. McElhenney, J. Yu

This study uses molecular dynamics simulations to show how SARS-CoV-2 RdRp traps non-cognate nucleotides during initial binding, contributing to replication fidelity.

bioRxiv · Sep 1, 2023Biophysics

Probing remdesivir nucleotide analogue insertion to SARS-CoV-2 RNA dependent RNA polymerase in viral replication

M. E. Romero, C. Long, D. La Rocco, A. M. Keerthi, D. Xu, J. Yu

This study computationally examines how remdesivir nucleotide analogue binds and inserts into SARS-CoV-2 RdRp, showing it has a lower energy barrier than ATP insertion.

bioRxiv · Jul 12, 2021Biophysics