A Novel Chronic in vivo Oral Cadmium Exposure-Washout Mouse Model for Studying Cadmium Toxicity and Complex Diabetogenic Effects
W. P. S. Wong, J. C. Wang, M. S. Meyers, N. J. Wang, R. A. Sponenburg, N. B. Allen, J. E. Edwards, M. El Muayed
This paper develops an in vivo oral cadmium exposure-washout mouse model that mimics human islet Cd bioaccumulation and shows sex-specific effects on glucose metabolism and insulin resistance.
bioRxiv · Feb 21, 2022Pharmacology & Toxicology