Cancer Associated Fibroblasts Mediate Cancer Progression and Remodel the Tumouroid Stroma
J. Pape, T. Magdeldin, K. Stamati, A. Nyga, M. Loizidou, M. Emberton, U. Cheema
This study shows that cancer-associated fibroblasts (CAFs) enhance cancer invasion and remodeling in a 3D in vitro model by upregulating specific factors and disrupting vascular networks.
bioRxiv · Nov 29, 2019Cancer Biology