A G-protein-biased S1P1 agonist, SAR247799, improved LVH and diastolic function in a rat model of metabolic syndrome
M. F. Evaristi, B. Poirier, X. Chenede, A.-M. Lefebvre, A. Roccon, F. Gillot, S. Beskee, A. Corbier, M.-P. Pruniaux-Harnist, P. Janiak, A. Parkar
This study shows that SAR247799, a G-protein-biased S1P1 agonist, improves left ventricular hypertrophy and diastolic function in a rat model of metabolic syndrome.
bioRxiv · Sep 14, 2021Pharmacology & Toxicology