The V-type H+-ATPase is targeted in anti-diuretic hormone control of the Malpighian (renal) tubules
F. Sajadi, M. F. Vergara-Martinez, J.-P. V. Paluzzi
This paper shows that CAPA inhibits diuretic hormone-induced secretion in mosquito Malpighian tubules by reducing V-type H+-ATPase activity through NOS/cGMP/PKG signaling and promoting VA complex dissociation.
Proceedings of the National Academy of Sciences · Dec 14, 2023Peer-reviewedPhysiology