A broad, exposome-type evaluation of xenobiotic phase II biotransformation in human biofluids by LC-MS/MS
Y. Fareed, D. Braun, M. Flasch, D. Globisch, B. Warth
The paper evaluates phase II biotransformation enzymes for xenobiotic deconjugation in human biofluids using LC-MS/MS, finding H. pomatia is most efficient overall but recombinant BGS is better for breast milk due to lower contamination.
bioRxiv · Jul 15, 2022Pharmacology & Toxicology