cAMP bursts control T cell directionality by actin cytoskeleton remodeling
M. Simao, F. Regnier, S. Taheraly, A. Fraisse, R. Tacine, M. Fraudeau, A. Benabid, V. Feuillet, M. Lambert, J. Delon, c. randriamampita
The paper shows that cAMP bursts from the leading edge of T cells drive actin remodeling, which is necessary for directional migration.
bioRxiv · Jul 6, 2020Immunology