Single-Molecule Dynamics of SARS-CoV-2 5' Cap Recognition by Human eIF4F
H. J. Hong, M. G. Guevara, E. Lin, S. E. O'Leary
This study investigates how eIF4F subunits coordinate to recognize the SARS-CoV-2 5' cap using single-molecule fluorescence, showing that eIF4A enhances cap accessibility and full complex formation affects eIF4E-cap interaction.
bioRxiv · May 26, 2021 · PreprintBiophysics