Author

M. G. Kearse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

B. Pastore· 1 shared D. J. Grove· 1 shared D. J. Levine· 1 shared M. R. Scarpitti· 1 shared W. Tang· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperBiochemistry

B. Pastore

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2 papers

Recent·Most cited

Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP

M. R. Scarpitti, B. Pastore, W. Tang, M. G. Kearse

This study shows FMRP stalls ribosomes and promotes no-go mRNA decay of specific transcripts, revealing a new role in FXS pathogenesis.

bioRxiv · Feb 2, 2024Biochemistry

Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits

D. J. Grove, D. J. Levine, M. G. Kearse

This study shows that increased eIF2A levels inhibit translation by sequestering 40S ribosomal subunits, using purified recombinant eIF2A and in vitro translation assays.

bioRxiv · Nov 18, 2022Biochemistry