A novel antibody against the furin cleavage site of SARS-CoV-2 spike protein: effects on proteolytic cleavage and ACE2 binding
M. G. Spelios, J. M. Capanelli, A. W. Li
This study develops an antibody targeting the furin cleavage site of SARS-CoV-2 spike protein, showing it blocks cleavage and ACE2 binding, potentially reducing viral infectivity.
bioRxiv · Feb 9, 2021Immunology