Author

M. Ghorbani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

J. B. Klauda· 3 shared B. R. Brooks· 2 shared M. Mantashloo· 1 shared M. Saffari· 1 shared P. B. Tiwari· 1 shared R. S. Sajjadi· 1 shared S. Ahmadi· 1 shared S. D. Mohammadi· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

J. B. Klauda

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Chlorpromazine inhibits EAG1 channels by altering the coupling between the PAS, CNBH and pore domains

M. Ghorbani, Z.-J. Wang, X. Chen, P. B. Tiwari, J. B. Klauda, T. I. I. Brelidze

This study shows chlorpromazine inhibits EAG1 channels by disrupting PAS-CNBH domain coupling, without affecting VSD movement.

bioRxiv · Feb 23, 2024 · PreprintBiophysics

Combination of arsenic trioxide epigallocatechin-3-gallate and Resveratrol synergistically suppresses the growth and invasion in Brain tumor cell lines

R. S. Sajjadi, S. Ahmadi, M. Mantashloo, S. Mehrpour Layeghi, Y. Asgari, M. Ghorbani, S. D. Mohammadi, M. Saffari

This study shows that combining arsenic trioxide, epigallocatechin-3-gallate, and resveratrol reduces brain tumor cell growth and invasion through apoptosis and decreased MMP expression.

bioRxiv · Oct 21, 2020 · PreprintCancer Biology

Exploring dynamics and network analysis of spike glycoprotein of SARS-COV-2

M. Ghorbani, B. R. Brooks, J. B. Klauda

This study uses MD simulations and network analysis to investigate the dynamics and shielding role of glycans in the SARS-CoV-2 spike protein, identifying key glycans and microdomains that hinder antibody access.

bioRxiv · Sep 28, 2020Biophysics

Critical Sequence Hot-spots for Binding of nCOV-2019 to ACE2 as Evaluated by Molecular Simulations

M. Ghorbani, B. R. Brooks, J. B. Klauda

This study identifies critical sequence hotspots for nCOV-2019 RBD binding to ACE2 using molecular simulations, highlighting implications for transmission, vaccine design, and drug development.

bioRxiv · Jun 27, 2020Biophysics