Author

M. Grady Freeman

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander A Brescia· 1 shared Benjamin D. HumphreysiD· 1 shared Katherine M. Holzem· 1 shared Krishnaben GajeraiD· 1 shared Mary A. SikiiD· 1 shared Pamela K. WoodardiD· 1 shared Patryk A. DabekiD· 1 shared Yuling ZhuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

Alexander A Brescia

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1 paper

Recent·Most cited

Cellular-Resolution Spatial Transcriptomics Reveals Laminar VSMC Phenotypic Remodeling and a Hypoxic Medial Core in Human Thoracic Aortic Dissection

Mary A. Siki, Krishnaben Gajera, Patryk A. Dabek, M. Grady Freeman, Yuling Zhu, Pamela K. Woodard, Alexander A Brescia, Benjamin D. Humphreys, Katherine M. Holzem

The paper uses spatial transcriptomics to identify hypoxia-adapted VSMC remodeling in human aortic dissection, linking it to interlamellar separation.

bioRxiv · Sep 30, 2026 · PreprintGenomics