Author

Patryk A. Dabek

Washington University in St. LouisORCID 0000-0002-9539-7092Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:clustering· 1 Assay:scATAC-seq· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alexander A Brescia· 1 shared Ashley HelmuthiD· 1 shared Benedikt ObermayeriD· 1 shared Benjamin D. HumphreysiD· 1 shared Caleb A. LareauiD· 1 shared David CapperiD· 1 shared Dieter BeuleiD· 1 shared Dustin K. Lieu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alexander A Brescia

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2 papers

Recent·Most cited

Cellular-Resolution Spatial Transcriptomics Reveals Laminar VSMC Phenotypic Remodeling and a Hypoxic Medial Core in Human Thoracic Aortic Dissection

Mary A. Siki, Krishnaben Gajera, Patryk A. Dabek, M. Grady Freeman, Yuling Zhu, Pamela K. Woodard, Alexander A Brescia, Benjamin D. Humphreys, Katherine M. Holzem

The paper uses spatial transcriptomics to identify hypoxia-adapted VSMC remodeling in human aortic dissection, linking it to interlamellar separation.

bioRxiv · Sep 30, 2026 · PreprintGenomics

Cryo-mtscATAC-seq for single-cell mitochondrial DNA genotyping and clonal tracing in archived human tissues

Maren Salla, Benedikt Obermayer, Marie Cotta, Ekaterina Friebel, Juliana Campo Garcia, Georgia Charalambous, Roemel Jeusep Bueno, Dustin K. Lieu, Patryk A. Dabek, Ashley Helmuth, George Tellides, Roland Assi, Katrin Bankov, Marco Lodrini, Hedwig E. Deubzer, , Leif S. Ludwig

The paper introduces Cryo-mtscATAC-seq to genotype mitochondrial DNA and trace clones in frozen human tissues, revealing clonal patterns in various diseases.

bioRxiv · Sep 17, 2025 · PreprintSystems Biology