Adaptive iron utilization compensates for the lack of an inducible uptake system in Naegleria fowleri and represents a potential target for therapeutic intervention
D. Arbon, K. Zeniskova, J. Mach, M. Grechnikova, R. Malych, P. Talacko, R. Sutak
This study shows that Naegleria fowleri uses mitochondrial iron to maintain respiration under iron starvation and suggests targeting this pathway for therapy.
bioRxiv · Sep 9, 2019Biochemistry