Cell BiologybioRxiv
YAP1 is essential for self-organized differentiation of pluripotent stem cells
K. Zeevaert, R. Goetzke, M. H. Elsafi Mabrouk…·W. Wagner
This study shows YAP1 is critical for germ layer specification in iPSCs, particularly in self-organized embryoid bodies, through NODAL pathway activation.
DOI 10.1016/j.bioadv.2023.213308